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Richard yu12/9/2023 ![]() ![]() Greater root accumulation (BCF = 1.01) of Zn and subsequent translocation to aerial parts (culm BCF = 0.58 and capsule BCF = 0.85) were exhibited in parents plants, whereas Pb was excluded from roots (BCF = 0.60) and very little translocation to aerial portions of the plant was observed (culm BCF = 0.02 and capsule BCF = 0.05). Seeds were exposed in the laboratory to incremental Zn (0.0❱.6 mM) and Pb (0.0❰.50 mM) for nine (9) days, and % germination, germination rate, root elongation and vigour index were assessed for the determination of tolerance. acutus seeds (F1 generation) were collected from F0 parent plants residing at eight locations of a contemporary sediment metal gradient (contaminated to uncontaminated) across the coast of NSW, Australia (Hunter river, Lake Macquarie and Georges River). We aimed to test the hypothesis that Juncus acutus individuals inhabiting metal-contaminated locations would experience elevated tolerance of offspring to metals compared to plants residing in locations with no metal contamination history. Halophytes residing in metal-contaminated saltmarsh habitats may employ strategies to enhance fitness of the next generation. Outstanding Contribution to Teaching AwardĬollege of Engineering, Science & Environment, University of Newcastleįaculty of Science | University of NewcastleĮndocrine disrupting chemicals (EDCs) in the aquatic environment: Their mechanisms of action and detection strategies School of Environmental and Life Sciences Professional Experience UON Appointment Title microarray and other genome-wide approaches) Pollution and contamination not elsewhere classified Bachelor of Science (Applied Biology)(Honours), City University of Hong Kong - China.PhD, City University of Hong Kong - China.Honours Coordinator, Bachelor of Environmental Science and Management (2011-2014) Head, Discipline of Environmental Science and Management (2017 - 2020)Ĭonvenor, Merit Pathway, Faculty of Science (2014 - 2020) At the basic science level, my research has led to the discovery of novel molecular mechanisms underlying (1) the regulation of gene expression induced by estrogenic compounds in oysters, (2) the inhibitory effects of aquatic hypoxia on fish reproduction (i.e., suppression of estrogen production and male-biased sex ratios) and food intake and (3) the modulation of sex steroid production (steroidogenesis) by organic environmental chemicals and their metabolites.Įcotoxicology, molecular toxicology, gene expression, endocrine disrupting chemicals (EDCs), aquatic hypoxia, environmental DNA (eDNA)ĮNVS2004 Ecology, ENVS3004 Ecotoxicology, SCIE1002 Multidisciplinary Laboratories, SCIE3500 Research Integrated Learningĭeputy Head (Teaching and Learning), School of Environmental and Life Sciences (2023 - Present) ![]() Examples include (1) an in-vivo reporter system for detecting estrogenic compounds using a transgenic marine medaka strain carrying the choriogenin (chg) promoter-GFP transgene (the technology was then commercialised as part of the environmental and food safety consultancy service in a Hong Kong-based biotechnology company), (2) development of the H295R steroidogenesis assay as an in-vitro screen for EDCs that interfere estrogen and testosterone production (this assay has become part of the OECD framework for the Testing and Assessment of Endocrine Disrupting Chemicals) and (3) development of real-time PCR assays for quantifying estrogen-induced gene expression (e.g., vitellogenin, vtg and estrogen receptor, er) in the native Australian oyster species, the Sydney rock oyster Saccostrea glomerata. Previously, my co-workers and I have developed sensitive molecular bioassays for environmental monitoring and risk assessment of compounds affecting sex hormone signalling and synthesis in both vertebrate and invertebrate systems. Overall, my research covers both basic science aimed at understanding the fundamental mechanisms of environmental toxicity and applied science concerned with the development of diagnostic tools for assessing and monitoring environmental toxicity and health impacts. In particular, I am interested in (1) understanding the molecular mechanisms of endocrine disruption caused by hypoxia and environmental chemicals, (2) developing bioassays for the screening and detection of endocrine-disrupting chemicals (EDCs) and (3) developing environmental DNA (eDNA) survey techniques to monitor aquatic wildlife populations. My primary research interests are in the molecular toxicology of environmental stressors and chemicals. Currently, I am a Senior Lecturer and Deputy Head of School (Teaching and Learning) in the School of Environmental and Life Sciences (SELS), College of Engineering, Science and Environment (CESE). Rudolf Wu, I continued to work in the same institution as a Lecturer until joining the University of Newcastle in 2009. ![]() After my postdoctoral training with Prof. I received my PhD from City University of Hong Kong in 2002. ![]()
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